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Identifying patients for RHAPSIDO® (remibrutinib)

 

 

Patient portrayal.

See the characteristics that can help you identify appropriate patients for RHAPSIDO

Which of your patients are ready for the next step in their treatment plan? Every patient’s experience with CSU is different, but there are key characteristics that can help you identify when to start RHAPSIDO.

Meet Emma, Charlotte, Alex, and George*

Quote graphic with patient portrait. Text reads: “Emma is looking for a treatment which may get her hives wellcontrolled that she can make a part of her daily routine.” Small text reads: “Patient portrayal.”

*Hypothetical patient profiles.

  • Age: 25 years  

  • Emma is a grad student who's constantly busy with school and activities and is looking for a treatment that may get her hives well-controlled, which she can make a part of her daily routine

Symptom Burden
  • Reported that recurring hives and itch frequently overlap with her daily life, including needing to cancel plans during flare-ups

  • Has been struggling with hives and itch for 3 months

Other Medical History
  • Anxiety

  • Depression

CSU Treatment History
  • Antihistamines up-dosed per guideline, but flares persist

  • Emergency care and short steroid course for severe flares

RHAPSIDO is for your patients like Emma who remain symptomatic despite antihistamines and are proactively searching for more relief from their CSU symptoms.1

Charlotte has tried 3 different antihistamines, but her hives keep coming back. Patient portrayal.

*Hypothetical patient profiles.

  • Age: 32 years  

  • Charlotte is a sous chef who is looking for a treatment that may relieve her hives and itch

Symptom Burden
  • Constantly worries about her severe symptoms during unpredictable flares

  • Intense itch has left her scratching through the day and night

  • Experiences occasional angioedema

Other Medical History
  • High-pressure job makes her prone to stress

  • Has been struggling with intense hives and itch day and night for 6 months

CSU Treatment History
  • Antihistamines up-dosed per guideline, but flares persist

  • Repeated steroid course for severe flares

  • Failed to get adequate response from prior biologic use

RHAPSIDO is for your patients like Charlotte who are looking for a treatment that may relieve their hives and itch.1

Alex is open to trying something else—especially if it's not an injection. Patient portrayal.

*Hypothetical patient profiles.

  • Age: 41 years  

  • Alex is a physical education teacher and coach with a busy away-game schedule, which makes managing an injectable treatment while on the road challenging

Symptom Burden
  • Flares of hives and itch bother him throughout the day

  • Has been struggling with flares of hives and itch almost daily for 9 months

Other Medical History
  • Insomnia

  • No history of autoimmune disease or other significant chronic comorbidities

CSU Treatment History
  • Repeated steroid courses for flares

  • Strong preference for oral therapy, due to busy schedule

RHAPSIDO is for your patients like Alex who remain symptomatic despite antihistamines but want to stay on an oral regimen.

George

*Hypothetical patient profiles.

  • Age: 48 years 

  • George is a truck driver with a busy schedule, which makes managing an injectable treatment while on the road challenging

Symptom Burden
  • Experiences hives and itch almost every day at work and at night

  • Has been struggling with CSU flares for the last 2 years

Other Medical History
  • Chronic back pain, managed with the help of his physician

CSU Treatment History
  • Antihistamines are his only prior treatment experience

RHAPSIDO is for patients like George who are looking for symptom relief from a treatment they can take on the go and within their busy work schedules.

RHAPSIDO targets BTK1

Relief from hives and itch1

BTK, Bruton’s tyrosine kinase; CSU, chronic spontaneous urticaria; MOA, mechanism of action.
Reference: 1. Rhapsido. Prescribing information. Novartis Pharmaceuticals Corp.