When antihistamines alone aren't enough1
CSU patient portrayal.
Chronic spontaneous urticaria (CSU) and symptomatic dermographism (SD) are two common types of chronic hives2,3
CSU is characterized by the spontaneous appearance of hives, angioedema, or both for >6 weeks due to no known external triggers.4
SD is specifically triggered by physical friction or rubbing on the skin, accompanied by hives and itch.5
~90% of patients with chronic hives have either CSU or SD.6
CSU and SD can last years and many patients remain symptomatic
CSU can last more than 5 years in 20% of patients.4,7
And up to 6.5 years on average in SD patients—requiring long-term treatment.3,4,7
Do you have patients with CSU whose symptoms remain despite high doses of antihistamines?
>50% of patients with CSU remain symptomatic, even
on increased doses of antihistamines8
≥66% of patients with CSU do not get onto advanced treatment despite up-dosing of antihistamines9,*
*Based on the Urticaria Voices study, a multinational, noninterventional, cross-sectional, online survey conducted from February 2022 to September 2022 in 582 patients with CSU. Overall, 33% of patients reported using biologics in combination with, or as an add-on to, other therapies.9
Breaking the cycle
Angioedema associated with CSU is typically non–life-threatening10,11
Typically, there is no risk of anaphylaxis. Angioedema in CSU does not usually involve airway compromise
Angioedema involves sudden tissue swelling. Swelling commonly involves lower dermis and subcutaneous tissue or mucous membranes (eg, lips, eyelids)
Rapid Recaps: CSU burden and treatment gaps
Hear from lead experts, Dr Michael Blaiss, Dr Adam Friedman, and Dr Priya Bansal, on the challenges and treatment gaps that patients with CSU face, including the impact of symptoms such as hives, itch, and/or angioedema.
Dr Blaiss, Dr Friedman, and Dr Bansal have been compensated for their time.